Mobilisation of funding for COVID-19 research in sub-Saharan Africa – 2020

The EDCTP “Emergency Funding Mechanism” allows rapid mobilisation of research funding based on a call for expressions of interest in exceptional and duly substantiated emergencies. On 11 March 2020, the WHO characterised COVID-19 as a pandemic, following alarming levels of infection spread and disease severity. Therefore, the EDCTP Association agreed to activate the emergency funding mechanism to support Research & Innovation Actions (RIAs) as part of the European response to the COVID-19 emergency. EDCTP invited proposals for RIAs to support research activities in sub-Saharan Africa to manage and/or prevent the spread of the current COVID-19 outbreak. 

 

See the corresponding call text

 

Call identifier: RIA2020EF

Africa Suitcaselab
Multi-country blinded study to evaluate the suitcase lab for rapid detection of SARS-CoV-2

Universität Leipzig, Germany, with partners from the Democratic Republic of the Congo, Ghana, Madagascar, Nigeria, Senegal, Sudan, Uganda, and the United Kingdom
Project coordinator: Dr Ahmed Abd El Wahed
Starting date: 01 August 2020
Duration: 14 months
EDCTP grant amount: EUR 500,000
Grant agreement: RIA2020EF-2937

AfriCover
Characterising transmission parameters of SARS-CoV-2 in peri-urban setting in Mozambique using population-based surveillance and high-throughput sero-assay

Prins Leopold Instituut voor Tropische Geneeskunde (ITM), Antwerp, Belgium, with partners from France, Mozambique, and the Netherlands
Project coordinator: Dr Marc-Alain Widdowson
Starting date: 01 June 2020
Duration: 23 months
EDCTP grant amount: EUR 499,990
Grant agreement: RIA2020EF-3031

AFRIDX
COVID-19 diagnostics for Africa

The Chancellor, Masters and Scholars of the University of Cambridge, (Cambridge, United Kingdom, with partners from Denmark, Ghana, and Sweden
Project coordinator: Prof. Elizabeth Hall
Starting date: 01 October 2020
Duration: 15 months
EDCTP grant amount: EUR 499,933
Grant agreement: RIA2020EF-2918

AIDCO
Important data on COVID-19 profile in Africa

Centre de recherches médicales de Lambaréné (CERMEL), Lambaréné, Gabon, with partners from Ethiopia, Gabon, Germany, the Netherlands, Senegal,  Mozambique, and Portugal
Project coordinator: Prof. Ayola Akim Adegnika
Starting date: 01 July 2020
Duration: 18 months
EDCTP grant amount: EUR 499,999
Grant agreement: RIA2020EF-2961

ANTICOV
Preparation of an open-label, randomised, comparative, adaptive, multi-country study to test the safety and efficacy of new therapeutic strategies against standard of care in mild SARS-CoV-2 patients in resource-constrained settings

Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland, with partners from the Democratic Republic of the Congo, Kenya, Spain, and the United Kingdom
Project coordinator: Dr Nathalie Strub-Wourgaft
Starting date: 01 May 2020
Duration: 06 months
EDCTP grant amount: EUR 200,000
Grant agreement: RIA2020EF-2975
Project web page

ASCENT
Acceleration of novel coronavirus serological test development and seroprevalence study: an African-European initiative

L’Institut national de la santé et de recherche médicale (Inserm), Paris, France, with partners from Burkina Faso, Guinée, the Netherlands, South Africa, Switzerland, and the United Kingdom
Project coordinator: Prof. Yves Levy
Starting date: 01 February 2020
Duration: 24 months
EDCTP grant amount: EUR 499,969
Grant agreement: RIA2020EF-2977

BCG-COVID-RCT
BCG vaccine to reduce absenteeism due to infectious diseases of health workers during the COVID-19 pandemic. A multi-centre randomised controlled trial

University of Southern Denmark, Odense M, Denmark, with partners from Cabo Verde, Guinea Bissau, Mozambique, and Portugal
Project coordinator: Prof. Christine Stabell-Benn
Starting date: 01 August 2020
Duration: 24 months
EDCTP grant amount: EUR 494,684
Grant agreement: RIA2020EF-3049
Project website

COREP
Determining the epidemiological parameters of COVID-19 through sero-surveillance with dried plasma spots and nested household transmission studies in rural Kenya and South Africa

Heidelberg University Hospital, Heidelberg, Germany, with partners from Australia, Kenya, South Africa, Spain
Project coordinator: Prof. Till Winfried Baernighausen
Starting date: 01 September 2020
Duration: 12 months
EDCTP grant amount: EUR 499,265
Grant agreement: RIA2020EF-3026

Core-NB
Collision of three global pandemics: the effect of tuberculosis and HIV on the epidemiological, clinical, virological and immunological trajectory of COVID-19 in Botswana and Namibia

Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften (FZB), Germany, with partners from Botswana, Namibia and United Kingdom
Project coordinator: Professor Stefan Niemann
Starting date: 3 August 2021
Duration: 18 months
Grant amount: EUR 499,997.25
Grant agreement: RIA2020EF-2963

COVAB
Investigating COVID-19 infectiousness and antibody evolution in COVID-19 patients in sub-Saharan Africa and Europe

King’s College London, London, United Kingdom, with partners in South Africa, Sweden, and the United Kingdom
Project coordinator: Dr Julie Fox
Starting date: 01 November 2020
Duration: 12 months
EDCTP grant amount: EUR 446,076
Grant agreement: RIA2020EF-3008

COVADIS
COVID-19 epidemic in West Africa: infection dynamics and diagnostic approaches

London School of Hygiene & Tropical Medicine, London, United Kingdom, with partners in Belgium, Burkina Faso, The Gambia, and the Netherlands
Project coordinator: Dr Annette Erhart
Starting date: 01 July 2020
Duration: 18 months
EDCTP grant amount: EUR 499,890
Grant agreement: RIA2020EF-3012

COVID-19 HCW
Surveillance among healthcare workers for SARS-Coronavirus-2-infection

Wit’s Health Consortium (Pty) Ltd., Johannesburg, South Africa, with partners in France and the United Kingdom
Project coordinator: Dr Marta Nunes
Starting date: 01 May 2020
Duration: 12 months
EDCTP grant amount: EUR 499,939
Grant agreement: RIA2020EF-3020

CSIGN
COVID surveillance intensification in Ghana Network

London School of  Hygiene & Tropical Medicine, London, United Kingdom, with partners from Ghana, Spain and The United Kingdom
Project coordinator: Dr Michael Marks
Starting date: 01 July 2020
Duration: 12 months
EDCTP grant amount: EUR 499,518
Grant agreement: RIA2020EF-2983

EXPERT-CoV2
Evaluation of molecular point-of-care Xpert® Xpress SARS-CoV-2 detection implementation in resource limited settings

National Institute for Medical Research (NIMR), Tanzania, with partners from Belgium, Burkina Faso, Democratic Republic of Congo, Denmark and Spain
Project coordinator: Dr Daniel Minja
Starting date: 1 July 2021
Duration: 24 months
Grant amount: EUR 500,000
Grant agreement: RIA2020EF-2990

HALT COVID-19
Natural history and laboratory tests for COVID-19 in South Africa

Centre for the AIDS programme of research in South Africa (CAPRISA), Durban, South Africa, with partners from Denmark, Germany and the Netherlands
Project coordinator: Professor Ayesha Kharsany
Starting date: 01 July 2020
Duration: 24 months
EDCTP grant amount: EUR 499,942
Grant agreement: RIA2020EF-2928

ImmunoCoV
Host immune responses to SARS-CoV-2: correlating kinetics with the natural history of infection

African Research Collaboration for Health Ltd., Kilifi, Kenya, with partners from Kenya, the Netherlands, and Sweden
Project coordinator: Dr Francis Ndungu
Starting date: 01 July 2020
Duration: 24 months
EDCTP grant amount: EUR 497,300
Grant agreement: RIA2020EF-3042

ITAIL-COVID-19
Integrated testing approaches and intensive laboratory training as strategy against SARS-CoV-2 spread in Brazzaville

Fondation Congolaise pour la Recherche Médicale (FCRM), Brazzaville, Republic of the Congo, with partners from Belgium, France, Germany, and the United Kingdom
Project coordinator: Dr Mathieu Ndounga
Starting date: 01 May 2020
Duration: 18 months
EDCTP grant amount: EUR 500,000
Grant agreement: RIA2020EF-2947

MA-CoV
Prevalence and impact of SARS-CoV-2 infection on maternal and infant health in African populations

Fundación Privada Instituto de Salud Global Barcelona (ISGLobal), Spain, with partners from Gabon, Germany and Mozambique
Project coordinator: Dr Raquel González Álvarez
Starting date: 1 July 2021
Duration: 21 months
Grant amount: EUR 499,999
Grant agreement: RIA2020EF-2956

MozCOVID
COVID-19 surveillance in rural Mozambique for prompt and effective response

Fundação Manhiça, Maputo, Mozambique, with partners from Mozambique, Spain and the United Kingdom
Project coordinator: Dr Inacio Mandomando
Starting date: 01 December 2020
Duration: 12 months
EDCTP grant amount: EUR 500,000
Grant agreement: RIA2020EF-3005

PERFECT-Study
Diagnostic Performance of Molecular and Serological Tests of SARS- CoV-2 on well-Characterised Specimens from COVID-19 Individuals in West and Central Africa: the “PERFECT-Study” (PERFormance Evaluation of COVID-19 Tests)

International Reference Centre Chantal Biya (CIRCB), Cameroon, with partners from Italy and France
Project coordinator: Dr Joseph Fokam
Starting date: 1 July 2021
Duration: 24 months
Grant amount: EUR 500,000
Grant agreement: RIA2020EF-3000

periCOVID-Africa
Understanding COVID-19 infections in pregnant women and their babies in Uganda, Kenya, Malawi, The Gambia and Mozambique

St George’s Hospital Medical School, London, United Kingdom, with partners from Kenya, Mozambique, Uganda, and the United Kingdom
Project coordinator: Dr LeDoare
Starting date: 01 November 2020
Duration: 18 months
EDCTP grant amount: EUR 499,934
Grant agreement: RIA2020EF-2926
Project website

Profile-COVID
Rapid diagnostic profiling of SARS-CoV-2 in the context of persistent immune activation in sub-Saharan Africa

Mekelle University, Mekelle, Ethiopia  with partners from Ethiopia, the Netherlands, and the United Kingdom
Project coordinator: Dr Dawit Wolday
Starting date: 01 July 2020
Duration: 12 months
EDCTP grant amount: EUR 499,580
Grant agreement: RIA2020EF-2905

RADIATES
Development, evaluation and impact of RT-LAMP diagnostics and sequence surveillance on SARS-CoV-2 transmission in South Africa

National Health Laboratory Service (NHLS), Johannesburg, South Africa with partners from South Africa, Sweden, and the United Kingdom
Project coordinator: Dr Jinal Bhiman
Starting date: 01 October 2020
Duration: 24 months
EDCTP grant amount: EUR 479,688
Grant agreement: RIA2020EF-3030

RE-BCG-CoV-19
BCG revaccination for healthcare workers in SARS-CoV-2 pandemic

Task Foundation NPC, Cape Town, South Africa with partners from the Netherlands, Spain, and Sweden
Project coordinator: Dr Andreas Diacon
Starting date: 17 April 2020
Duration: 24 months
EDCTP grant amount: EUR 500,000
Grant agreement: RIA2020EF-2968
Project webpage

STRESSCO
Strengthening epidemiological surveillance in Benin and Burkina Faso for an effective response to COVID-19

Institut de Recherche Clinique du Bénin, Calavi, Benin, with partners from Benin, Burkina Faso, France, and Spain
Project coordinator: Dr Ahlin Achille Massougbodji
Starting date: 01 December 2020
Duration: 18 months
EDCTP grant amount: EUR 499,994
Grant agreement: RIA2020EF-2923

TraCE
Transmission of COVID-19 in crowded environments

Desmond Tutu Health Foundation NPC, Cape Town, South Africa, with partners from the Netherlands, South Africa, and the United Kingdom
Project coordinator: Prof. Linda-Gail Bekker
Starting date: 01 July 2020
Duration: 12 months
EDCTP grant amount: EUR 496,233
Grant agreement: RIA2020EF-2981

TREATS-COVID
Understanding the epidemiology of SARS-CoV-2 and the interrelation of COVID-19 with TB and HIV in Zambia

ZAMBART, Lusaka, Zambia, with partners from France, the Netherlands, and the United Kingdom
Project coordinator: Dr Kwame Shanaube
Starting date: 01 July 2020
Duration: 18 months
EDCTP grant amount: EUR 500,000
Grant agreement: RIA2020EF-3004