///Paediatric drug formulations for poverty-related diseases - 2019

Paediatric drug formulations for poverty-related diseases – 2019

Funding under this call aims to support research on the adaptation of existing medicinal products (drugs), including off-patent products, to the specific needs of children (0-17 years of age) for any poverty-related disease within the scope of the EDCTP2 programme. Proposals were to include one (or more) clinical trials conducted in sub-Saharan Africa to assess the safety, efficacy and pharmacokinetics of the drug(s), and/or the development of age-appropriate formulations.

Call identifier: RIA2019PD

See the corresponding call text

ACOZI-KIDS
Towards a pediatric indication for children between 1 and 14 years of age for a safe, effective, all-oral single-dose treatment formulation of acoziborole for first and second stage gambiense human African trypanosomiasis (g-HAT)

Drugs for Neglected Diseases initiative, Geneva, Switzerland, with partners from the Democratic Republic of the Congo, France, Guinea, and Portugal 
Project coordinator: Dr Antoine Tarral
Starting date: 01 October 2020
Duration: 60 months
EDCTP grant amount: EUR 2,999,107
Grant agreement: RIA2019PD-2890

DPP
Developing paediatric primaquine

Chancellor, Masters and Scholars of the University of Oxford, Oxford, United Kingdom, with partners from Burkina Faso, Ethiopia, and France
Project coordinator: Dr W.R.J. Taylor
Starting date: 01 September 2020
Duration: 56 months
EDCTP grant amount: EUR 3,489,896
Grant agreement: RIA2019PD-2893
Project website

MiniMox
Treatment for all: Developing a paediatric formulation moxidectin for neglected infectious diseases

Luxembourg Institute of Health, Luxembourg, Luxembourg, with partners from Cameroon, Germany, Ghana, and the United Kingdom
Project coordinator: Dr Michel Vaillant
Starting date: 01 January 2021
Duration: 42 months
EDCTP grant amount: EUR 2,112,690
Grant agreement: RIA2019PD-2880

PedMAb
Phase I/II study to determine Safety and Pharmacokinetics of subcutaneous administration of potent and broad anti HIV-1 neutralizing monoclonal antibodies, given to HIV-1 exposed neonates and infants

Ospedale San Raffaele SRL, Italy, with partners from France, Norway and South Africa
Project coordinator: Dr Gabriella Scarlatti
Starting date: 1 May 2021
Duration: 42 months
Grant amount: EUR 3,965,161
Grant agreement: RIA2019PD-2887

UNIVERSAL
Pharmacokinetic and safety studies of new antiretroviral formulations: expediting UNIVERSAL first and second line regimens for all children living with HIV in Africa

Fondazione PENTA ONLUS (PENTA), Italy, with partners from Cameroon, Cote d’Ivoire, France, Mali, the Netherlands, Senegal, Spain, Switzerland, Uganda, United Kingdom, United States and Zimbabwe
Project coordinator: Professor Carlo Giaquinto
Starting date: 1 January 2021
Duration: 60 months
Grant amount: EUR 3,999,818.75
Grant agreement: RIA2019PD-2882